Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans.

Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans.

The 18kDa Translocator Protein (TSPO) is the most commonly used tissue-specific marker of inflammation in positron emission tomography (PET) studies. It is expressed in myeloid cells such as microglia and macrophages, and in rodent myeloid cells expression increases with cellular activation. We asse...

Full description

Bibliographic Details
Main Authors: Owen, DR, Narayan, N, Wells, L, Healy, L, Smyth, E, Rabiner, EA, Galloway, D, Williams, JB, Lehr, J, Mandhair, H, Peferoen, LA, Taylor, PC, Amor, S, Antel, JP, Matthews, PM, Moore, CS
Format: Journal article
Language:English
Published: SAGE Publications 2017

Similar Items

Similar Items