The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity.

The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity.

Glycosylation of macrolide antibiotics confers host cell immunity from endogenous and exogenous agents. The Streptomyces antibioticus glycosyltransferases, OleI and OleD, glycosylate and inactivate oleandomycin and diverse macrolides including erythromycin, respectively. The structure of these enzym...

Full description

Bibliographic Details
Main Authors:	Bolam, D, Roberts, S, Proctor, MR, Turkenburg, J, Dodson, E, Martinez-Fleites, C, Yang, M, Davis, B, Davies, G, Gilbert, H
Format:	Journal article
Language:	English
Published:	2007

Similar Items

Probing the breadth of macrolide glycosyltransferases: in vitro remodeling of a polyketide antibiotic creates active bacterial uptake and enhances potency.
by: Yang, M, et al.
Published: (2005)

Addition of macrolide antibiotics for hospital treatment of community-acquired pneumonia
by: Wei, J, et al.
Published: (2024)

Adverse events in people taking macrolide antibiotics versus placebo for any indication
by: Hansen, M, et al.
Published: (2019)

Sugar mimetics: Multicomponent glycosyltransferase inhibitors
by: Lucas, R, et al.
Published: (2005)

Treatment of pharmaceutical wastewater containing macrolide antibiotics by up-flow anarobic stage reactor (UASR) /
by: Shreeshivadasan Chelliapan 542025
Published: (2006)

Susceptibility of bacterial isolates from community-acquired infections in sub-Saharan Africa and Asia to macrolide antibiotics.
by: Lubell, Y, et al.
Published: (2011)

Susceptibility of bacterial isolates from community-acquired infections in sub-Saharan Africa and Asia to macrolide antibiotics
by: Lubell, Y, et al.
Published: (2011)

METHOD DEVELOPMENT OF MACROLIDE AND PLEUROMUTILIN ANTIBIOTICS IN LIQUID MANURE SAMPLES BY LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY
by: , Juwita Ayu Manggalarini, et al.
Published: (2013)

Aminoglycoside and macrolide resistance in Burkholderia pseudomallei.
by: Simpson, A, et al.
Published: (1999)

Exploring the mechanisms of macrolides in cystic fibrosis.
by: Equi, A, et al.
Published: (2006)

Structural dissection and high-throughput screening of mannosylglycerate synthase.
by: Flint, J, et al.
Published: (2005)

Functional and informatics analysis enables glycosyltransferase activity prediction
by: Yang, M, et al.
Published: (2018)

Stereochemical Divergence of Polyprenol Phosphate Glycosyltransferases
by: Eichler, Jerry, et al.
Published: (2019)

Determination of aminoglycoside, Β-lactam, macrolides, quinolones, sulfonamides, and tetracycline (veterinary antibiotics) in broiler chicken manure and land applied manure
by: Ho, Yu Bin, et al.
Published: (2009)

Glycomimetic inhibitors of mycobacterial glycosyltransferases: targeting the TB cell wall.
by: Lucas, R, et al.
Published: (2008)

Antibiotic resistance and host immune evasion in Staphylococcus aureus mediated by a metabolic adaptation
by: Jiang, J-H, et al.
Published: (2019)

A quantitative study of the Golgi retention of glycosyltransferases
by: Sun, Xiuping, et al.
Published: (2021)

Macrolides in critically ill patients with Middle East Respiratory Syndrome
by: Arabi, Y, et al.
Published: (2019)

Macrolide synthesis through intramolecular oxidative cross‐coupling of alkenes
by: Jiang, Bing, et al.
Published: (2020)

Antibiotic-Induced Changes to the Host Metabolic Environment Inhibit Drug Efficacy and Alter Immune Function
by: McCloskey, Douglas, et al.
Published: (2019)

Prevalence of macrolide resistance mechanisms in Streptococcus pneumoniae isolates from a multicenter antibiotic resistance surveillance study conducted in the United States in 1994-1995.
by: Shortridge, V, et al.
Published: (1999)

A courageous blueprint
by: Zainal Abidin, Irwan Shah
Published: (2015)

Blueprint keterjaminan makanan
by: Saad, Wan Zuhainis, et al.
Published: (2024)

Blueprints for life or death.
by: Jones, E
Published: (2001)

The geometric blueprint of perovskites
by: Filip, M, et al.
Published: (2018)

Programmed blueprint reading /
by: 395464 Coover, Shriver L.
Published: (1970)

The strategic management blueprint /
by: 261776 Dobson, Paul, et al.
Published: (1993)

Blueprint reading for welders
Published: (1978)

Mechanistic evidence for a front-side, SNi-type reaction in a retaining glycosyltransferase.
by: Lee, S, et al.
Published: (2011)

Potential cyclodextrin glycosyltransferase producer from locally isolated bacteria
by: Ramli, Norhayati, et al.
Published: (2010)

Optimization of cyclodextrin glycosyltransferase production by response surface methodology approach.
by: Ai-Noi, Sauvaphap, et al.
Published: (2008)

Effect of operating conditions on characterization and stabilization of cyclodextrin glycosyltransferase (CGTASE)
by: Nur 'Izzaty Hazera, Nazar
Published: (2016)

Priming and processing glycosyltransferases in bacterial N-linked glycosylation pathways
by: Lukose, Vinita
Published: (2016)

Case series of long-term macrolide therapy effect on eosinophil count in COPD
by: Asciak, R, et al.
Published: (2017)

No need to rewrite education blueprint
by: Abd Razak, Dzulkifli
Published: (2008)

Building trades blueprint reading /
by: 395537 Sundberg, Elmer W.
Published: (1972)

Blueprint reading for the mechanical trades /
by: 401557 Sachdeva, B. R.
Published: (1979)

The blueprint language of the machine industries /
by: 460878 Spencer, Henry Cecil, et al.
Published: (1947)

Elementary blueprint reading for machinists /
by: 401695 Taylor, David L.
Published: (1981)

BLUEPRINT READING FOR... [lukisan teknik]