The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity.

The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity.

Glycosylation of macrolide antibiotics confers host cell immunity from endogenous and exogenous agents. The Streptomyces antibioticus glycosyltransferases, OleI and OleD, glycosylate and inactivate oleandomycin and diverse macrolides including erythromycin, respectively. The structure of these enzym...

Podrobná bibliografie
Hlavní autoři:	Bolam, D, Roberts, S, Proctor, MR, Turkenburg, J, Dodson, E, Martinez-Fleites, C, Yang, M, Davis, B, Davies, G, Gilbert, H
Médium:	Journal article
Jazyk:	English
Vydáno:	2007

Podobné jednotky

Probing the breadth of macrolide glycosyltransferases: in vitro remodeling of a polyketide antibiotic creates active bacterial uptake and enhances potency.
Autor: Yang, M, a další
Vydáno: (2005)

Pathogen- and Host-Directed Anti-Inflammatory Activities of Macrolide Antibiotics
Autor: Helen C. Steel, a další
Vydáno: (2012-01-01)

Voltammetric study of the partitioning of macrolide antibiotics at the water/nitrobenzene interface. Relationship to the pharmacokinetic profiling of macrolides
Autor: Zoran Mandic
Vydáno: (2014-09-01)

Macrolide antibiotic therapy in patients with cystic fibrosis
Autor: MH Schöni
Vydáno: (2003-05-01)

Administration of macrolide antibiotics increases cardiovascular risk
Autor: Yang Wu, a další
Vydáno: (2023-02-01)

Degradation of macrolide antibiotic in water by heterogeneous photocatalysis
Autor: A. Ounnar, a další
Vydáno: (2017-12-01)

Functional and informatics analysis enables glycosyltransferase activity prediction
Autor: Yang, M, a další
Vydáno: (2018)

Inhibiting Effect of Macrolide Polyene Antibiotics on Reproduction of Viruses
Autor: A. A. Bagirova, a další
Vydáno: (2020-05-01)

Context-specific action of macrolide antibiotics on the eukaryotic ribosome
Autor: Maxim S. Svetlov, a další
Vydáno: (2021-05-01)

The evolution of substrate discrimination in macrolide antibiotic resistance enzymes
Autor: Andrew C. Pawlowski, a další
Vydáno: (2018-01-01)

Sugar mimetics: Multicomponent glycosyltransferase inhibitors
Autor: Lucas, R, a další
Vydáno: (2005)

Eritrea's blueprint for trachoma elimination: A home-grown model for sustainable impact
Autor: Gilbert Baayenda, a další
Vydáno: (2025-03-01)

The provident planner : a blueprint for homes, communities and lifestyles /
Autor: 363971 Rasbach, Roger
Vydáno: (1976)

Association of Macrolide Resistance Genotypes and Synergistic Antibiotic Combinations for Combating Macrolide-Resistant MRSA Recovered from Hospitalized Patients
Autor: Amr S. Bishr, a další
Vydáno: (2021-07-01)

Autoinducer Analogs Can Provide Bactericidal Activity to Macrolides in <i>Pseudomonas aeruginosa</i> through Antibiotic Tolerance Reduction
Autor: Mizuki Abe, a další
Vydáno: (2021-12-01)

Addition of macrolide antibiotics for hospital treatment of community-acquired pneumonia
Autor: Wei, J, a další
Vydáno: (2024)

Mechanism of Action of Macrolide Antibiotic Filipin on Cell and Lipid Membranes
Autor: A. A. Samedova, a další
Vydáno: (2020-05-01)

Scaffold Modifications in Erythromycin Macrolide Antibiotics. A Chemical Minireview
Autor: Kjell Undheim
Vydáno: (2020-08-01)

Research on the treatment of Pseudomonas aeruginosa pneumonia in children by macrolide antibiotics
Autor: Huang Xu-qiang, a další
Vydáno: (2015-01-01)

Bioassay-guided evolution of glycosylated macrolide antibiotics in Escherichia coli.
Autor: Ho Young Lee, a další
Vydáno: (2007-02-01)

Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics
Autor: Bertrand Beckert, a další
Vydáno: (2021-07-01)

Additional corticosteroids or alternative antibiotics for the treatment of macrolide-resistant pneumonia
Autor: Eun-Ae Yang, a další
Vydáno: (2017-08-01)

Examining the role of macrolides and host immunity in combatting filarial parasites
Autor: Doug S. Carithers
Vydáno: (2017-04-01)

Structural dissection and high-throughput screening of mannosylglycerate synthase.
Autor: Flint, J, a další
Vydáno: (2005)

A Blueprint for Cancer-Related Inflammation and Host Innate Immunity
Autor: Lucia García-López, a další
Vydáno: (2021-11-01)

How to read electrical blueprints /
Autor: 219560 Heine, Gilbert M., a další
Vydáno: (1954)

Phenotypic Resistance of (MRSA) Clinical Isolates to Some Macrolide Antibiotic Groups
Autor: Ali Yaseen, a další
Vydáno: (2023-12-01)

Molecular Imprinted Polymers for Macrolides, Aminoglycosides and Some Other Biosynthetic Antibiotics
Autor: M. I. Yakhkind, a další
Vydáno: (2020-05-01)

In Vitro Impact of Macrolide Antibiotics on the Viability of Selected Mammalian Cell Lines
Autor: Eva Tvrdá, a další
Vydáno: (2023-09-01)

Mechanisms of Resistance to Macrolide Antibiotics among <i>Staphylococcus aureus</i>
Autor: Maria Miklasińska-Majdanik
Vydáno: (2021-11-01)

Macrolide antibiotics activate the integrated stress response and promote tumor proliferation
Autor: Xin Yu, a další
Vydáno: (2023-03-01)

Macrolide antibiotics and their place in therapy of upper respiratory tract infections therapy
Autor: A. Y. Ovchinnikov, a další
Vydáno: (2016-12-01)

Differential trypanocidal activity of novel macrolide antibiotics; correlation to genetic lineage.
Autor: Carolina Aquilino, a další
Vydáno: (2012-01-01)

Place of Semisynthetic Penicillins and Macrolides in Antibiotic Therapy for Respiratory Infections in Children
Autor: A.Ye. Abaturov, a další
Vydáno: (2014-09-01)

Blueprint
Autor: Fariba Jaffary
Vydáno: (2023-03-01)

Engineering of cyclodextrin glycosyltransferase /
Autor: Dijkhuizen, L.

Effector glycosyltransferases in Legionella
Autor: Yury eBelyi, a další
Vydáno: (2011-04-01)

Increase in Pneumococcus Macrolide Resistance, USA
Autor: Lauri A. Hicks, a další
Vydáno: (2010-05-01)

Clinical efficacy of macrolide antibiotics in mycoplasma pneumoniae pneumonia carrying a macrolide-resistant mutation in the 23 S rRNA gene in pediatric patients
Autor: Mengyuan He, a další
Vydáno: (2024-07-01)

Mechanistic evidence for a front-side, SNi-type reaction in a retaining glycosyltransferase.
Autor: Lee, S, a další
Vydáno: (2011)