Regression reconstruction from a retrospective sample

The simplest form of retrospective study allows the reconstruction of the dependence be- tween a binary outcome, Y, representing the contrast between cases and controls, and one or more explanatory variables. A different objective for such situations is considered, in which there are distinct explan...

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書目詳細資料
Main Authors: Kartsonaki, C, Cox, DR
格式: Journal article
語言:English
出版: Elsevier 2020
實物特徵
總結:The simplest form of retrospective study allows the reconstruction of the dependence be- tween a binary outcome, Y, representing the contrast between cases and controls, and one or more explanatory variables. A different objective for such situations is considered, in which there are distinct explanatory variables, say (W, X) determining Y . Reconstruction of the originating distribution of (W, X) from the case-control data is considered for both continuous and binary variables. Emphasis is on the linear regression coefficient of W on X. That coefficient, but not the relevant intercept, shows considerable stability, as shown by theory and simulations. An approximation to the value of the coefficient not conditioning on Y is given.