Studies on the reaction of nitric oxide with the hypoxia-inducible factor prolyl hydroxylase domain 2 (EGLN1)

Studies on the reaction of nitric oxide with the hypoxia-inducible factor prolyl hydroxylase domain 2 (EGLN1)

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The hypoxic response in animals is mediated via the transcription factor hypoxia-inducible factor (HIF). An oxygen-sensing component of the HIF system is provided by Fe(II) and 2-oxoglutarate-dependent oxygenases that catalyse the posttranslational hydroxylation of the HIF-α subunit. It is proposed...

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Bibliographic Details
Main Authors:	Chowdhury, R, Flashman, E, Mecinović, J, Kramer, H, Kessler, B, Frapart, Y, Boucher, J, Clifton, I, McDonough, M, Schofield, C
Format:	Journal article
Language:	English
Published:	2011

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