Pharmacological disruption of the outer limiting membrane leads to increased retinal integration of transplanted photoreceptor precursors.
Retinal degeneration is the leading cause of untreatable blindness in the developed world. Cell transplantation strategies provide a novel therapeutic approach to repair the retina and restore sight. Previously, we have shown that photoreceptor precursor cells can integrate and form functional photo...
Những tác giả chính: | West, E, Pearson, R, Tschernutter, M, Sowden, J, Maclaren, R, Ali, R |
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Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
2008
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Những quyển sách tương tự
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Targeted disruption of outer limiting membrane junctional proteins (Crb1 and ZO-1) increases integration of transplanted photoreceptor precursors into the adult wild-type and degenerating retina.
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