Nucleophosmin and p14ARF mediated regulation of p53

<p>Tumour initiation and progression occur due to oncogenic mutations that also contribute to therapeutic resistance in many human tumours. Mutations activating the "PI3K/AKT" signalling pathway and inactivating the "<em>TP53</em>" tumour suppressor gene are com...

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Bibliographic Details
Main Author: Abraham, A
Other Authors: O'Neill, E
Format: Thesis
Language:English
Published: 2015
Subjects:

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