Nucleophosmin and p14ARF mediated regulation of p53

Nucleophosmin and p14ARF mediated regulation of p53

<p>Tumour initiation and progression occur due to oncogenic mutations that also contribute to therapeutic resistance in many human tumours. Mutations activating the "PI3K/AKT" signalling pathway and inactivating the "<em>TP53</em>" tumour suppressor gene are com...

Deskribapen osoa

Xehetasun bibliografikoak
Egile nagusia:	Abraham, A
Beste egile batzuk:	O'Neill, E
Formatua:	Thesis
Hizkuntza:	English
Argitaratua:	2015
Gaiak:	Oncology

Antzeko izenburuak

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The ubiquitin ligase TRIM21 regulates mutant p53 accumulation and gain of function in cancer
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Overexpression of CCDC69 activates p14ARF/MDM2/p53 pathway and confers cisplatin sensitivity
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p14ARF induces the relocation of HDM2 and p53 to extranucleolar sites that are targeted by PML bodies and proteasomes
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Nucleophosmin Protein Dephosphorylation by DUSP3 Is a Fine-Tuning Regulator of p53 Signaling to Maintain Genomic Stability
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The expression level of ARF and p53 in AML patients, and their relation to patients' outcome
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Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade
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Argitaratua: (2024-04-01)

Molecular genetic analysis in B-cell Lymphomas : a focus on the p53 pathway and p16INK4a
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Mimicking p14ARF phosphorylation influences its ability to restrain cell proliferation.
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Genetic variation in MDM2 and p14ARF and susceptibility to salivary gland carcinoma.
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Argitaratua: (2021-01-01)

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Argitaratua: (2010)

SIVA-1 enhances acquired chemotherapeutic drug resistance of gastric cancer in vivo by regulating the ARF/MDM2/p53 pathway
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Argitaratua: (2024-01-01)

Correction: Mimicking p14ARF Phosphorylation Influences Its Ability to Restrain Cell Proliferation.
nork: Maria Vivo, et al.
Argitaratua: (2013-01-01)

The identification and analysis of molecular biomarkers in the p53 tumour suppressor pathway that affect cancer progression in humans
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p14ARF forms meso-scale assemblies upon phase separation with NPM1
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Argitaratua: (2024-11-01)

Correction: Mimicking p14ARF Phosphorylation Influences Its Ability to Restrain Cell Proliferation
Argitaratua: (2013-01-01)

P14/ARF-Positive Malignant Pleural Mesothelioma: A Phenotype With Distinct Immune Microenvironment
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Gemcitabine therapeutically disrupts essential SIRT1-mediated p53 repression in atypical teratoid/rhabdoid tumors
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Argitaratua: (2024-09-01)

Decreased Mdm2 expression inhibits tumor development and extends survival independent of Arf and dependent on p53.
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