Determining possible shared genetic architecture between myopia and primary open-angle glaucoma

Purpose:To determine genetic correlations between common myopia and primary open-angle glaucoma (POAG). Methods:We tested the association of myopia polygenic risk scores (PRSs) with POAG and POAG endophenotypes using two studies: the Australian & New Zealand Registry of Advanced Glaucoma (AN...

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Hlavní autoři: Iglesias, AI, Ong, JS, Khawaja, AP, Gharahkhani, P, Tedja, MS, Verhoeven, VJM, Bonnemaijer, PWM, Wolfs, RCW, Young, TL, Jansonius, NM, Craig, JE, Stambolian, D, Van Duijn, CM, Macgregor, S, Klaver, CCW
Další autoři: International Glaucoma Genetics Consortium
Médium: Journal article
Jazyk:English
Vydáno: Association for Research in Vision and Ophthalmology 2019