Hypertrophic cardiomyopathy:a paradigm for myocardial energy depletion.

Hypertrophic cardiomyopathy:a paradigm for myocardial energy depletion.

Genetic analysis of hypertrophic cardiomyopathy (HCM), a mendelian form of cardiac hypertrophy, indicates that the primary defect is in sarcomeric function. However, the initial proposal that depressed myocardial contraction leads to a 'compensatory' hypertrophy has proven inconsistent wit...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Ashrafian, H, Redwood, C, Blair, E, Watkins, H
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2003

Παρόμοια τεκμήρια

Myocardial dysfunction in hypertrophic cardiomyopathy.
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Ascertainment strategies and genotype:phenotype correlations in hypertrophic cardiomyopathy.
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Metabolic perturbations in the pathogenesis of hypertrophic cardiomyopathy
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The genetics of hypertrophic cardiomyopathy: Teare redux.
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Functional analysis of hypertrophic cardiomyopathy missense mutations in the light meromyosin region of beta myosin heavy chain
ανά: Redwood, C, κ.ά.
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Inherited cardiomyopathies.
ανά: Watkins, H, κ.ά.
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Inherited cardiomyopathies.
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Disease pathways and novel therapeutic targets in hypertrophic cardiomyopathy.
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Mutations in the gamma(2) subunit of AMP-activated protein kinase cause familial hypertrophic cardiomyopathy: evidence for the central role of energy compromise in disease pathogenesis.
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ανά: Kramer, CM, κ.ά.
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ανά: Ariga, R, κ.ά.
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Mutations of the light meromyosin domain of the beta-myosin heavy chain rod in hypertrophic cardiomyopathy.
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Novel mutations in cardiac MYBPC3 causing early onset malignant hypertrophic cardiomyopathy
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Is DNA testing for hypertrophic cardiomyopathy cost-effective?
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Mutations in cis can confound genotype-phenotype correlations in hypertrophic cardiomyopathy.
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Double mutations in CIS can confound genotype-phenotype correlations in hypertrophic cardiomyopathy
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Novel mutations in cardiac MYPBC3 cause early onset malignant hypertrophic cardiomyopathy (HCM)
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Progression of myocardial fibrosis in hypertrophic cardiomyopathy: mechanisms and clinical implications
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Blunted myocardial oxygenation response during vasodilator stress in patients with hypertrophic cardiomyopathy.
ανά: Karamitsos, T, κ.ά.
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METABOLIC ALTERATION IN HYPERTROPHIC CARDIOMYOPATHY (METAL-HCM STUDY): RANDOMISED DOUBLE BLINDED PLACEBO CONTROLLED TRIAL OF PERHEXILINE THERAPY IN PATIENT WITH HYPERTROPHIC CARDIOMYOPATHY
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Dilated and hypertrophic cardiomyopathy mutations in troponin and alpha-tropomyosin have opposing effects on the calcium affinity of cardiac thin filaments.
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Impaired left ventricular energy metabolism in hypertrophic cardiomyopathy is not due to fibrosis.
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