The human cytoplasmic RNA terminal U-transferase ZCCHC11 targets histone mRNAs for degradation.
Inhibition of eukaryotic DNA replication leads to the rapid suppression of histone synthesis, via 3' uridylation of cytoplasmic histone mRNAs followed by their Lsm1-7-mediated decapping and degradation. Here we show that the human cytoplasmic RNA terminal U-transferase ZCCHC11, recently implica...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2011
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