Deoxyguanosine is a TLR7 agonist

Toll-like receptor 7 (TLR7) is an innate immune sensor for single-strand RNA (ssRNA). Recent structural analysis revealed that TLR7 has an additional binding site for nucleosides such as guanosine and is activated when both guanosine and ssRNA bind. The nucleoside binding site also accommodates imid...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Davenne, T, Bridgeman, A, Rigby, R, Rehwinkel, J
Formatua: Journal article
Hizkuntza:English
Argitaratua: Wiley 2019