Deoxyguanosine is a TLR7 agonist

Deoxyguanosine is a TLR7 agonist

Toll-like receptor 7 (TLR7) is an innate immune sensor for single-strand RNA (ssRNA). Recent structural analysis revealed that TLR7 has an additional binding site for nucleosides such as guanosine and is activated when both guanosine and ssRNA bind. The nucleoside binding site also accommodates imid...

Bibliografske podrobnosti
Main Authors:	Davenne, T, Bridgeman, A, Rigby, R, Rehwinkel, J
Format:	Journal article
Jezik:	English
Izdano:	Wiley 2019

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