Disruption of copper homeostasis due to a mutation of Atp7a delays the onset of prion disease.

Disruption of copper homeostasis due to a mutation of Atp7a delays the onset of prion disease.

Copper influences the pathogenesis of prion disease, but whether it is beneficial or detrimental remains controversial. Copper homeostasis is also essential for normal physiology, as highlighted by the spectrum of diseases caused by disruption of the copper transporting enzymes ATP7A and ATP7B. Here...

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Chi tiết về thư mục
Những tác giả chính:	Siggs, O, Cruite, J, Du, X, Rutschmann, S, Masliah, E, Beutler, B, Oldstone, M
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2012

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