Temporal dynamics of CD8+ T cell effector responses during primary HIV infection.

The loss of HIV-specific CD8+ T cell cytolytic function is a primary factor underlying progressive HIV infection, but whether HIV-specific CD8+ T cells initially possess cytolytic effector capacity, and when and why this may be lost during infection, is unclear. Here, we assessed CD8+ T cell functio...

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Bibliographic Details
Main Authors:	Demers, KR, Makedonas, G, Buggert, M, Eller, MA, Ratcliffe, SJ, Goonetilleke, N, Li, CK, Eller, LA, Rono, K, Maganga, L, Nitayaphan, S, Kibuuka, H, Routy, J-P, Slifka, MK, Haynes, BF, McMichael, AJ, Bernard, NF, Robb, ML, Betts, MR
Other Authors:	Douek, DC
Format:	Journal article
Language:	English
Published:	Public Library of Science 2016

Temporal dynamics of CD8+ T cell effector responses during primary HIV infection.

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