Insulin-like growth factor-1 (IGF-1), insulin-like growth factor-binding protein-3 (IGFBP-3) and breast cancer risk: Observational and Mendelian randomization analyses with ~430,000 women

<p><strong>Background:</strong><br /> Epidemiological evidence supports a positive association between circulating insulin-like growth factor-1 (IGF-1) concentrations and breast cancer risk, but both the magnitude and causality of this relationship are uncertain. We conducted...

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Bibliographic Details
Main Authors: Murphy, N, Knuppel, A, Papadimitriou, N, Martin, RM, Tsilidis, KK, Smith-Byrne, K, Fensom, G, Perez-Cornago, A, Travis, RC, Key, TJ, Gunter, MJ
Format: Journal article
Language:English
Published: Elsevier 2020