Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4+ T cells through p65 and H2B phosphorylation

Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4+ T cells through p65 and H2B phosphorylation

Memory T cells are characterized by their rapid transcriptional programs upon re-stimulation. This transcriptional memory response is facilitated by permissive chromatin, but exactly how the permissive epigenetic landscape in memory T cells integrates incoming stimulatory signals remains poorly unde...

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Bibliographic Details
Main Authors: Li, J, Hardy, K, Phetsouphanh, C, Tu, WJ, Sutcliffe, EL, McCuaig, R, Sutton, CR, Zafar, A, Munier, CML, Zaunders, JJ, Xu, Y, Theodoratos, A, Tan, A, Lim, PS, Knaute, T, Masch, A, Zerweck, J, Brezar, V, Milburn, PJ, Dunn, J, Casarotto, MG, Turner, SJ, Seddiki, N, Kelleher, AD, Rao, S
Format: Journal article
Language:English
Published: Company of Biologists 2018

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