Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4+ T cells through p65 and H2B phosphorylation
Memory T cells are characterized by their rapid transcriptional programs upon re-stimulation. This transcriptional memory response is facilitated by permissive chromatin, but exactly how the permissive epigenetic landscape in memory T cells integrates incoming stimulatory signals remains poorly unde...
المؤلفون الرئيسيون: | Li, J, Hardy, K, Phetsouphanh, C, Tu, WJ, Sutcliffe, EL, McCuaig, R, Sutton, CR, Zafar, A, Munier, CML, Zaunders, JJ, Xu, Y, Theodoratos, A, Tan, A, Lim, PS, Knaute, T, Masch, A, Zerweck, J, Brezar, V, Milburn, PJ, Dunn, J, Casarotto, MG, Turner, SJ, Seddiki, N, Kelleher, AD, Rao, S |
---|---|
التنسيق: | Journal article |
اللغة: | English |
منشور في: |
Company of Biologists
2018
|
مواد مشابهة
-
PKC-Theta is a novel SC35 splicing factor regulator in response to T cell activation
حسب: Robert Duncan Mccuaig, وآخرون
منشور في: (2015-11-01) -
Single-cell profiling of lineage determining transcription factors in antigen-specific CD4+ T cells reveals unexpected complexity in recall responses during immune reconstitution
حسب: Phetsouphanh, C, وآخرون
منشور في: (2017) -
PKC-θ: hitting the bull's eye.
حسب: Dustin, M
منشور في: (2011) -
The Novel PKCθ from Benchtop to Clinic
حسب: Rouba Hage-Sleiman, وآخرون
منشور في: (2015-01-01) -
Assessment of TCR-induced Sumoylation of PKC-θ
حسب: Xudong Wang, وآخرون
منشور في: (2016-10-01)