Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4+ T cells through p65 and H2B phosphorylation

Memory T cells are characterized by their rapid transcriptional programs upon re-stimulation. This transcriptional memory response is facilitated by permissive chromatin, but exactly how the permissive epigenetic landscape in memory T cells integrates incoming stimulatory signals remains poorly unde...

Celý popis

Podrobná bibliografie
Hlavní autoři:	Li, J, Hardy, K, Phetsouphanh, C, Tu, WJ, Sutcliffe, EL, McCuaig, R, Sutton, CR, Zafar, A, Munier, CML, Zaunders, JJ, Xu, Y, Theodoratos, A, Tan, A, Lim, PS, Knaute, T, Masch, A, Zerweck, J, Brezar, V, Milburn, PJ, Dunn, J, Casarotto, MG, Turner, SJ, Seddiki, N, Kelleher, AD, Rao, S
Médium:	Journal article
Jazyk:	English
Vydáno:	Company of Biologists 2018

Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4+ T cells through p65 and H2B phosphorylation

Podobné jednotky