The C-terminus of Apc does not influence intestinal adenoma development or progression

The C-terminus of Apc does not influence intestinal adenoma development or progression

Diğer sürümleri göster (1)

Adenomatous polyposis coli (APC) mutations are found in most colorectal tumours. These mutations are almost always protein-truncating, deleting both central domains that regulate Wnt signalling and C-terminal domains that interact with the cytoskeleton. The importance of Wnt dysregulation for colore...

Detaylı Bibliyografya
Asıl Yazarlar:	Lewis, A, Davis, H, Deheragoda, M, Pollard, P, Nye, E, Jeffery, R, Segditsas, S, East, P, Poulsom, R, Stamp, G, Wright, N, Tomlinson, I
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	2012

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