Potential intermediates for incorporation of polyhydroxylated prolines into combinatorial libraries

Bicyclic 2 and monocyclic 6 2-amino-1,4-lactones provide divergent intermediates for subsequent incorporation of polyhydroxylated prolines into combinatorial amide libraries. The X-ray crystal structure of an azidolactone, combined with molecular modelling, rationalises the very different behaviour...

Полное описание

Библиографические подробности
Главные авторы: Long, D, Frederiksen, S, Marquess, D, Lane, A, Watkin, D, Winkler, D, Fleet, G
Формат: Journal article
Язык:English
Опубликовано: 1998