Functional studies of BCL11A: characterization of the conserved BCL11A-XL splice variant and its interaction with BCL6 in nuclear paraspeckles of germinal center B cells.

Functional studies of BCL11A: characterization of the conserved BCL11A-XL splice variant and its interaction with BCL6 in nuclear paraspeckles of germinal center B cells.

BACKGROUND: Chromosomal aberrations of BCL11A at 2p16.1 have been reported in a variety of B-cell malignancies and its deficiency in mice leads to a profound block in B-cell development. RESULTS: Alternative pre-mRNA splicing of BCL11A produces multiple isoforms sharing a common N-terminus. The most...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Liu, H, Ippolito, G, Wall, J, Niu, T, Probst, L, Lee, B, Pulford, K, Banham, A, Stockwin, L, Shaffer, A, Staudt, L, Das, C, Dyer, M, Tucker, P
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	2006

Antzeko izenburuak

Gains of the proto-oncogene BCL11A and nuclear accumulation of BCL11A(XL) protein are frequent in primary mediastinal B-cell lymphoma.
nork: Weniger, M, et al.
Argitaratua: (2006)

IN VIVO ENRICHMENT OF REGULATORY T CELLS BY BCL-2/BCL-XL INHIBITION PROMOTES TOLERANCE IN ALLOTRANSPLANTATION
nork: Gabriel, S, et al.
Argitaratua: (2013)

The BCL11AXL transcription factor: its distribution in normal and malignant tissues and use as a marker for plasmacytoid dendritic cells.
nork: Pulford, K, et al.
Argitaratua: (2006)

Molecular interaction of tumor suppressor protein p53 and anti-apoptotic proteins Bcl-2 and Bcl-XL.
nork: Yoon, Ho Sup.
Argitaratua: (2010)

UK-2A ANALOGUES: POTENTIAL INHIBITORS OF BCL-XL
nork: , AMJ Putra, M Hanafi, Y Anita
Argitaratua: (2007)

Dynamics of Bcl-xL in water and membrane : molecular simulations
nork: Maity, Atanu., et al.
Argitaratua: (2014)

Novel, simplified alpha-helix mimetics targeted to Bcl-xL
nork: Rodriguez, J, et al.
Argitaratua: (2007)

NMR approach to characterize Bcl-xl structure and interaction mechanism in membrane state
nork: Liu, Wei
Argitaratua: (2014)

Synchronised phosphorylation of BNIP3, Bcl-2 and Bcl-xL in response to microtubule-active drugs is JNK-independent and requires a mitotic kinase.
nork: Mellor, H, et al.
Argitaratua: (2010)

Frequent gains of REL and BCL11A in mediastinal B-cell lymphoma selectively provoke up-regulated RNA and protein expression
nork: Weniger, M, et al.
Argitaratua: (2007)

Potent and Specific Peptide Inhibitors of Human Pro-Survival Protein Bcl-xL
nork: Ryan, Jeremy, et al.
Argitaratua: (2017)

Structure of Bcl-xL-Bak peptide complex : recognition between regulators of Apoptosis
nork: Meadows, Robert P., et al.
Argitaratua: (2012)

Locating Herpesvirus Bcl-2 Homologs in the Specificity Landscape of Anti-Apoptotic Bcl-2 Proteins
nork: Foight, Glenna W., et al.
Argitaratua: (2017)

Anti-Apoptotic Proteins Mcl-1 And Bcl-Xl Are Crucial For Nasopharyngeal Carcinoma Cell Survival
nork: Abdul Rahman, Siti Fairus
Argitaratua: (2022)

Metabolic Regulation of Protein N-Alpha-Acetylation by Bcl-xL Promotes Cell Survival
nork: Yi, Caroline H., et al.
Argitaratua: (2014)

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death
nork: Yoon, Ho Sup, et al.
Argitaratua: (2012)

Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport
nork: Rajan, Sreekanth, et al.
Argitaratua: (2015)

Molecular basis of Bcl-XL-p53 interaction : insights from molecular dynamics simulations
nork: Bharatham, Nagakumar, et al.
Argitaratua: (2012)

Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-κB Inhibition
nork: Arbab, I.A., et al.
Argitaratua: (2012)

BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis
nork: Canver, Matthew C., et al.
Argitaratua: (2016)

BCL11A intellectual developmental disorder: defining the clinical spectrum and genotype-phenotype correlations
nork: Peron, A, et al.
Argitaratua: (2024)

The novel role of the B-cell lymphoma/leukemia 11A (BCL11A) gene in β-thalassaemia treatment
nork: Lai, Mei I, et al.
Argitaratua: (2023)

Transiently Activated Human Regulatory T Cells Upregulate BCL-XL Expression and Acquire a Functional Advantage in vivo
nork: Issa, F, et al.
Argitaratua: (2019)

PERBANDINGAN EKSPRESI PROTEIN Bcl-XL SEL TROFOBLAS PLASENTA ANTARA PREEKLAMPSIA BERAT DENGAN KEHAMILAN NORMOTENSI
nork: , Arsi Palupi, et al.
Argitaratua: (2013)

IMMUNOCYTOCHEMICAL STUDY OF THE BCL-2 GENE-PRODUCT
nork: Pezzella, F, et al.
Argitaratua: (1990)

Solution structure of the antiapoptotic protein bcl-2
nork: Petros, Andrew M., et al.
Argitaratua: (2012)

Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation
nork: Basak, Anindita, et al.
Argitaratua: (2021)

A de novo substitution in BCL11B leads to loss of interaction with transcriptional complexes and craniosynostosis
nork: Goos, J, et al.
Argitaratua: (2019)

The MDM2-binding region in the transactivation domain of p53 also acts as a Bcl-XL-binding motif
nork: Xu, Huibin, et al.
Argitaratua: (2012)

The N-terminal domain of tumor suppressor p53 is involved in the molecular interaction with the anti-apoptotic protein Bcl-Xl
nork: Xu, Huibin, et al.
Argitaratua: (2012)

Expression of the bcl-2 oncogene protein is not specific for the 14;18 chromosomal translocation.
nork: Pezzella, F, et al.
Argitaratua: (1990)

The pattern of Ki-67 and bcl-2 expression in Lymphoid Malignancies
nork: Wang, P.L., et al.
Argitaratua: (1997)

What is the value of bcl-2 protein detection for histopathologists?
nork: Pezzella, F, et al.
Argitaratua: (1995)

Mutations in Bcl10 are very rare in colorectal cancer.
nork: Stone, J, et al.
Argitaratua: (1999)

Ekspresi protein bcl-2 pada karsinoma nasofaring
nork: , OYONG, et al.
Argitaratua: (2005)

Bcl-2 phosphorylation and implications in apoptosis in cancer cells
nork: Xia, Yan
Argitaratua: (2011)

Synthesis and characterisation of the persistent radical [BCl2(bipy)]*.
nork: Mansell, S, et al.
Argitaratua: (2010)

Transcriptional silencing of γ-globin by BCL11A involves long-range interactions and cooperation with SOX6
nork: Xu, Jian, et al.
Argitaratua: (2014)

BCL11B Drives Human Mammary Stem Cell Self-Renewal In Vitro by Inhibiting Basal Differentiation
nork: Cabrera, Janel R., et al.
Argitaratua: (2018)

Biochemical and structural studies on the molecular interaction between P53 transcriptional activation domain and anti-apoptotic protein BCL-XL
nork: Xu, Huibin
Argitaratua: (2009)