Amerind ancestry, socioeconomic status and the genetics of type 2 diabetes in a Colombian population.

The "thrifty genotype" hypothesis proposes that the high prevalence of type 2 diabetes (T2D) in Native Americans and admixed Latin Americans has a genetic basis and reflects an evolutionary adaptation to a past low calorie/high exercise lifestyle. However, identification of the gene varian...

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Main Authors: Campbell, D, Parra, M, Duque, C, Gallego, N, Franco, L, Tandon, A, Hünemeier, T, Bortolini, C, Villegas, A, Bedoya, G, McCarthy, M, Price, A, Reich, D, Ruiz-Linares, A
格式: Journal article
语言:English
出版: Public Library of Science 2012