Shared mechanisms in physiological and pathological nucleoplasmic reticulum formation
The mammalian nuclear envelope (NE) can develop complex dynamic membrane-bounded invaginations in response to both physiological and pathological stimuli. Since the formation of these nucleoplasmic reticulum (NR) structures can occur during interphase, without mitotic NE breakdown and reassembly, so...
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| Format: | Journal article |
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Taylor and Francis
2016
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| _version_ | 1797051841473675264 |
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| author | Drozdz, M Vaux, D |
| author_facet | Drozdz, M Vaux, D |
| author_sort | Drozdz, M |
| collection | OXFORD |
| description | The mammalian nuclear envelope (NE) can develop complex dynamic membrane-bounded invaginations in response to both physiological and pathological stimuli. Since the formation of these nucleoplasmic reticulum (NR) structures can occur during interphase, without mitotic NE breakdown and reassembly, some other mechanism must drive their development. Here we consider models for deformation of the interphase NE, together with the evidence for their potential roles in NR formation. |
| first_indexed | 2024-03-06T18:25:07Z |
| format | Journal article |
| id | oxford-uuid:07ad9e7f-0f5e-40db-8971-cbddc17b4ab7 |
| institution | University of Oxford |
| last_indexed | 2024-03-06T18:25:07Z |
| publishDate | 2016 |
| publisher | Taylor and Francis |
| record_format | dspace |
| spelling | oxford-uuid:07ad9e7f-0f5e-40db-8971-cbddc17b4ab72022-03-26T09:08:53ZShared mechanisms in physiological and pathological nucleoplasmic reticulum formationJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:07ad9e7f-0f5e-40db-8971-cbddc17b4ab7Symplectic Elements at OxfordTaylor and Francis2016Drozdz, MVaux, DThe mammalian nuclear envelope (NE) can develop complex dynamic membrane-bounded invaginations in response to both physiological and pathological stimuli. Since the formation of these nucleoplasmic reticulum (NR) structures can occur during interphase, without mitotic NE breakdown and reassembly, some other mechanism must drive their development. Here we consider models for deformation of the interphase NE, together with the evidence for their potential roles in NR formation. |
| spellingShingle | Drozdz, M Vaux, D Shared mechanisms in physiological and pathological nucleoplasmic reticulum formation |
| title | Shared mechanisms in physiological and pathological nucleoplasmic reticulum formation |
| title_full | Shared mechanisms in physiological and pathological nucleoplasmic reticulum formation |
| title_fullStr | Shared mechanisms in physiological and pathological nucleoplasmic reticulum formation |
| title_full_unstemmed | Shared mechanisms in physiological and pathological nucleoplasmic reticulum formation |
| title_short | Shared mechanisms in physiological and pathological nucleoplasmic reticulum formation |
| title_sort | shared mechanisms in physiological and pathological nucleoplasmic reticulum formation |
| work_keys_str_mv | AT drozdzm sharedmechanismsinphysiologicalandpathologicalnucleoplasmicreticulumformation AT vauxd sharedmechanismsinphysiologicalandpathologicalnucleoplasmicreticulumformation |