Living without creatine: Unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice

Living without creatine: Unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice

Εμφάνιση άλλων εκδόσεων (1)

RATIONALE:: Creatine is thought to be involved in the spatial and temporal buffering of ATP in energetic organs such as heart and skeletal muscle. Creatine depletion affects force generation during maximal stimulation, while reduced levels of myocardial creatine are a hallmark of the failing heart,...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Lygate, C, Aksentijevic, D, Dawson, D, Ten Hove, M, Phillips, D, De Bono, J, Medway, D, Sebag-Montefiore, L, Hunyor, I, Channon, K, Clarke, K, Zervou, S, Watkins, H, Balaban, R, Neubauer, S
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2013

Παρόμοια τεκμήρια

Living without creatine: unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice.
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Regulation of Myocardial Creatine Uptake by Intra- and Extracellular Creatine Levels
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Elevated Myocardial Creatine Protects Against Ischemia/Reperfusion Injury by Improving Cardiac Energetics
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Creatine uptake in mouse hearts with genetically altered creatine levels.
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Chronic creatine kinase deficiency eventually leads to congestive heart failure, but severity is dependent on genetic background, gender and age
ανά: Lygate, C, κ.ά.
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Chronic creatine kinase deficiency eventually leads to congestive heart failure, but severity is dependent on genetic background, gender and age.
ανά: Lygate, C, κ.ά.
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Adaptations to Maintain Energy Homeostasis Compensate for Creatine-Deficiency in GAMT Knockout Mice Following Myocardial Infarction, but May Contribute to Early Mitochondrial Pathology During Aging
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Cardiac phenotype of mitochondrial creatine kinase knockout mice is modified on a pure C57BL/6 genetic background.
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Supra-normal (phospho-)creatine levels lead to heart failure in mice overexpressing the cardiac creatine transporter - a longitudinal study
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Ribose supplementation alone or with elevated creatine does not preserve high energy nucleotides or cardiac function in the failing mouse heart
ανά: Faller, K, κ.ά.
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REGULATION OF CELLULAR CREATINE HOMEOSTASIS: A ROLE FOR THIOREDOXIN INTERACTING PROTEIN (TXNIP)
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Changes in creatine transporter function during cardiac maturation in the rat.
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Complete absence of creatine but unaltered ATP levels in hearts from AGAT knockout mice
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Supernormal myocardial creatine and phosphocreatine concentrations lead to cardiac hypertrophy and heart failure - Insights from creatine transporter over-expression transgenic mice
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Unchanged Mitochondrial Organization and Compartmentation in Creatine Deficient GAMT-/- Mouse Heart
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Regulation of myocardial creatine uptake capacity in genetically altered mouse models
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Supranormal myocardial creatine and phosphocreatine concentrations lead to cardiac hypertrophy and heart failure: insights from creatine transporter-overexpressing transgenic mice.
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Creatine reduces mitochondrial permeability transition pore opening in response to oxidative stress in vitro
ανά: Zervou, S, κ.ά.
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Chronic Creatine-deficiency is not the Underlying Cause of Cardiac Dysfunction in Mice Lacking the Creatine Biosynthetic Enzyme Arginine: glycine Amidinotransferase
ανά: Lygate, C, κ.ά.
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The creatine kinase energy transport system in the failing mouse heart.
ανά: Lygate, C, κ.ά.
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Mice over-expressing the myocardial creatine transporter develop progressive heart failure and show decreased glycolytic capacity.
ανά: Phillips, D, κ.ά.
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Impaired cardiac contractile function in AGAT knockout mice devoid of creatine is rescued by homoarginine but not creatine
ανά: Faller, K, κ.ά.
Έκδοση: (2017)

Unchanged mitochondrial organization and compartmentation of high-energy phosphates in creatine-deficient GAMT-/- mouse hearts.
ανά: Branovets, J, κ.ά.
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The creatine kinase energy transport system in the failing mouse heart
ανά: Lygate, C, κ.ά.
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Myocardial creatine levels do not influence response to acute oxidative stress in isolated perfused heart
ανά: Aksentijević, D, κ.ά.
Έκδοση: (2014)

Ribose Supplementation Alone or with Elevated Creatine Does Not Preserve High Energy Nucleotides or Cardiac Function in the Failing Mouse Heart.
ανά: Kiterie M E Faller, κ.ά.
Έκδοση: (2013-01-01)

New insights into the creatine kinase-phosphocreatine energy buffer and transport system using mouse models of altered creatine content
ανά: Lygate, C, κ.ά.
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Mechanisms of creatine depletion in chronically failing rat heart.
ανά: Ten Hove, M, κ.ά.
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Hearts from gamt ko mice lack phospho-creatine, show reduced inotropic reserve and are more prone to ischemia
ανά: ten Hove, M, κ.ά.
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Influence of homoarginine on creatine accumulation and biosynthesis in the mouse
ανά: Lygate, CA, κ.ά.
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GUANIDINOACETATE N-METHYLTRANSFERASE KNOCKOUT MICE EXHIBIT NORMAL LEFT VENTRICULAR REMODELLING, HAEMODYNAMICS AND SURVIVAL AFTER MYOCARDIAL INFARCTION DESPITE LACK OF PHOSPHOCREATINE
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Influence of homoarginine on creatine accumulation and biosynthesis in the mouse
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Creatine transporter activity and content in the rat heart supplemented by and depleted of creatine.
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