HES6 drives a critical AR transcriptional programme to induce castration‐resistant prostate cancer through activation of an E2F1‐mediated cell cycle network
<p style="text-align:justify;"> Castrate‐resistant prostate cancer (CRPC) is poorly characterized and heterogeneous and while the androgen receptor (AR) is of singular importance, other factors such as c‐Myc and the E2F family also play a role in later stage disease. HES6 is a trans...
Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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Format: | Journal article |
Published: |
EMBO Press
2014
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