HES6 drives a critical AR transcriptional programme to induce castration‐resistant prostate cancer through activation of an E2F1‐mediated cell cycle network

HES6 drives a critical AR transcriptional programme to induce castration‐resistant prostate cancer through activation of an E2F1‐mediated cell cycle network

<p style="text-align:justify;"> Castrate‐resistant prostate cancer (CRPC) is poorly characterized and heterogeneous and while the androgen receptor (AR) is of singular importance, other factors such as c‐Myc and the E2F family also play a role in later stage disease. HES6 is a trans...

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Bibliographic Details
Main Authors: Ramos-Montoya, A, Lamb, A, Russell, R, Carroll, T, Jurmeister, S, Galeano-Dalmau, N, Massie, C, Boren, J, Bon, H, Theodorou, V, Vias, M, Shaw, G, Sharma, N, Ross-Adams, H, Scott, H, Vowler, S, Howat, W, Warren, A, Wooster, R, Mills, I, Neal, D
Format: Journal article
Published: EMBO Press 2014

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