Identification of Tyr58 as the proton donor in the aspartate-alpha-decarboxylase reaction.

The decarboxylation of L-aspartate by E. coli L-aspartate-alpha-decarboxylase (ADC) is shown to occur with retention of configuration; analysis of the protein structure identifies Tyr58 as the proton donor in the decarboxylation mechanism.

Dettagli Bibliografici
Autori principali: Saldanha, SA, Birch, L, Webb, M, Nabbs, B, von Delft, F, Smith, A, Abell, C
Natura: Journal article
Pubblicazione: 2001