The toll-like receptor 4 Asp299Gly variant: no influence on LPS responsiveness or susceptibility to pulmonary tuberculosis in The Gambia.
SETTING: Tuberculosis (TB) remains a major cause of morbidity and mortality worldwide. Studies in a murine model of pulmonary TB have identified a role for Toll-like receptor 4 (TLR4) in the development of chronic lung infection with Mycobacterium tuberculosis. The Asp299Gly polymorphism in the huma...
Main Authors: | Newport, M, Allen, A, Awomoyi, A, Dunstan, S, McKinney, E, Marchant, A, Sirugo, G |
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Format: | Journal article |
Language: | English |
Published: |
2004
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