Treatment interruption in chronic HIV-1 infection: does it deliver?
PURPOSE OF REVIEW: This review sets out to overview treatment interruption in chronic HIV-1 infection: what treatment interruption promised, results from recent trials, and what the future holds. RECENT FINDINGS: Recent studies have produced mixed results; several trials have been prematurely halte...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
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2007
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| _version_ | 1797051912255700992 |
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| author | Willberg, C Nixon, D |
| author_facet | Willberg, C Nixon, D |
| author_sort | Willberg, C |
| collection | OXFORD |
| description | PURPOSE OF REVIEW: This review sets out to overview treatment interruption in chronic HIV-1 infection: what treatment interruption promised, results from recent trials, and what the future holds. RECENT FINDINGS: Recent studies have produced mixed results; several trials have been prematurely halted, whereas others have reported more positive outcomes. One consistent finding has been the identification of the CD4 T-cell count nadir as a critical parameter in determining the outcome of treatment interruption. SUMMARY: The use of treatment interruption is still controversial, but it is becoming clear that certain individuals could benefit, and partial treatment interruption strategies warrant further investigation. |
| first_indexed | 2024-03-06T18:25:56Z |
| format | Journal article |
| id | oxford-uuid:07f7100a-b683-47c8-8f7c-ce08227871d0 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T18:25:56Z |
| publishDate | 2007 |
| record_format | dspace |
| spelling | oxford-uuid:07f7100a-b683-47c8-8f7c-ce08227871d02022-03-26T09:10:25ZTreatment interruption in chronic HIV-1 infection: does it deliver?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:07f7100a-b683-47c8-8f7c-ce08227871d0EnglishSymplectic Elements at Oxford2007Willberg, CNixon, D PURPOSE OF REVIEW: This review sets out to overview treatment interruption in chronic HIV-1 infection: what treatment interruption promised, results from recent trials, and what the future holds. RECENT FINDINGS: Recent studies have produced mixed results; several trials have been prematurely halted, whereas others have reported more positive outcomes. One consistent finding has been the identification of the CD4 T-cell count nadir as a critical parameter in determining the outcome of treatment interruption. SUMMARY: The use of treatment interruption is still controversial, but it is becoming clear that certain individuals could benefit, and partial treatment interruption strategies warrant further investigation. |
| spellingShingle | Willberg, C Nixon, D Treatment interruption in chronic HIV-1 infection: does it deliver? |
| title | Treatment interruption in chronic HIV-1 infection: does it deliver? |
| title_full | Treatment interruption in chronic HIV-1 infection: does it deliver? |
| title_fullStr | Treatment interruption in chronic HIV-1 infection: does it deliver? |
| title_full_unstemmed | Treatment interruption in chronic HIV-1 infection: does it deliver? |
| title_short | Treatment interruption in chronic HIV-1 infection: does it deliver? |
| title_sort | treatment interruption in chronic hiv 1 infection does it deliver |
| work_keys_str_mv | AT willbergc treatmentinterruptioninchronichiv1infectiondoesitdeliver AT nixond treatmentinterruptioninchronichiv1infectiondoesitdeliver |