Treatment interruption in chronic HIV-1 infection: does it deliver?

Treatment interruption in chronic HIV-1 infection: does it deliver?

PURPOSE OF REVIEW: This review sets out to overview treatment interruption in chronic HIV-1 infection: what treatment interruption promised, results from recent trials, and what the future holds. RECENT FINDINGS: Recent studies have produced mixed results; several trials have been prematurely halte...

Full description

Bibliographic Details
Main Authors:	Willberg, C, Nixon, D
Format:	Journal article
Language:	English
Published:	2007

Similar Items

Immunological biomarkers predict HIV-1 viral rebound after treatment interruption
by: Hurst, J, et al.
Published: (2015)

Stimulation of HIV-specific cellular immunity by structured treatment interruption fails to enhance viral control in chronic HIV infection.
by: Oxenius, A, et al.
Published: (2002)

Immune and viral correlates of "secondary viral control" after treatment interruption in chronically HIV-1 infected patients.
by: Ellen Van Gulck, et al.
Published: (2012-01-01)

The immunological and virological consequences of planned treatment interruptions in children with HIV infection
by: Klein, N, et al.
Published: (2013)

Interruption of antiretroviral therapy to augment immune control of chronic HIV-1 infection: risk without reward.
by: Abbas, U, et al.
Published: (2002)

Imaging and biopsy of HIV-infected individuals undergoing analytic treatment interruption
by: Chuen-Yen Lau, et al.
Published: (2022-08-01)

Evaluating lncRNA Expression Patterns during HIV-1 Treatment Interruption
by: Tinus Schynkel, et al.
Published: (2023-01-01)

Association of differentiation state of CD4+ T cells and disease progression in HIV-1 perinatally infected children.
by: Sharp, E, et al.
Published: (2012)

Risk factors for interruption in treatment among HIV-infected adolescence attending health care and treatment clinics in Tanzania
by: Expeditho L. Mtisi, et al.
Published: (2023-03-01)

Results of antiretroviral treatment interruption and intensification in advanced multi-drug resistant HIV infection from the OPTIMA trial.
by: Holodniy, M, et al.
Published: (2011)

Immunodominance of HIV-1 specific CD8+ T-cell responses is related to disease progression rate in vertically infected adolescents.
by: Sharp, E, et al.
Published: (2011)

TILT: a randomized controlled trial of interruption of antiretroviral therapy with or without interleukin-2 in HIV-1 infected individuals.
by: Angus, B, et al.
Published: (2008)

Interrupção do acompanhamento clínico ambulatorial de pacientes infectados pelo HIV The interruption of outpatient clinical care of HIV-infected patients
by: Celeste S Rodrigues, et al.
Published: (2003-04-01)

Immunity to HIV-1 is influenced by continued natural exposure to exogenous virus.
by: Willberg, C, et al.
Published: (2008)

Can clinical algorithms deliver an accurate diagnosis of HIV infection in infancy?
by: Stephanie A. Jones, et al.

Can clinical algorithms deliver an accurate diagnosis of HIV infection in infancy?
by: Stephanie A. Jones, et al.
Published: (2005-07-01)

Rates and determinants of virologic and immunological response to HAART resumption after treatment interruption in HIV-1 clinical practice.
by: Touloumi, G, et al.
Published: (2008)

Buprenorphine Increases HIV-1 Infection In Vitro but Does Not Reactivate HIV-1 from Latency
by: Germán Gustavo Gornalusse, et al.
Published: (2021-07-01)

CTL responses to HIV-1 during acute and chronic infection
by: Culshaw, A, et al.
Published: (2008)

Macrophage infection via selective capture of HIV-1-infected CD4+ T cells.
by: Baxter, A, et al.
Published: (2014)

Predicting Treatment Interruption Among People Living With HIV in Nigeria: Machine Learning Approach
by: Matthew-David Ogbechie, et al.
Published: (2023-05-01)

Thymic Output and CD4 T-Cell Reconstitution in HIV-Infected Children on Early and Interrupted Antiretroviral Treatment: Evidence from the Children with HIV Early Antiretroviral Therapy Trial
by: Lewis, J, et al.
Published: (2017)

Does a youth intern programme strengthen HIV service delivery in South Africa? An interrupted time‐series analysis
by: Deanna Tollefson, et al.
Published: (2023-04-01)

Antiretroviral Therapy Interruption (ATI) in HIV-1 Infected Patients Participating in Therapeutic Vaccine Trials: Surrogate Markers of Virological Response
by: Lorna Leal, et al.
Published: (2020-08-01)

A prospective trial of structured treatment interruptions in human immunodeficiency virus infection.
by: Fagard, C, et al.
Published: (2003)

Relevance of HIV-1-specific CD4+ helper T-cell responses during structured treatment interruptions in patients with CD4+ T-cell nadir above 400/mm3.
by: Plana, M, et al.
Published: (2004)

Does the church deliver? Perceptions amongst South Africans about the role of the church in the HIV/AIDS field
by: PJ van Dyk, et al.
Published: (2007-09-01)

Immunodominant HIV-1 Cd4+ T cell epitopes in chronic untreated clade C HIV-1 infection.
by: Ramduth, D, et al.
Published: (2009)

Does captopril interrupt compensatory ovarian changes in hemispayed rats
by: Chatterjjee, Rita, et al.
Published: (1999)

Characterization of anti-HIV-1 neutralizing and binding antibodies in chronic HIV-1 subtype C infection.
by: Archary, D, et al.
Published: (2012)

Characterization of anti-HIV-1 neutralizing and binding antibodies in chronic HIV-1 subtype C infection
by: Archary, D, et al.
Published: (2012)

Drivers of HIV treatment interruption: Early findings from community-led monitoring program in Haiti.
by: Soeurette Policar, et al.
Published: (2023-01-01)

Drivers of HIV treatment interruption: Early findings from community-led monitoring program in Haiti
by: Soeurette Policar, et al.
Published: (2023-01-01)

Impact of Analytical Treatment Interruption on Burden and Diversification of HIV Peripheral Reservoir: A Pilot Study
by: Rossana Scutari, et al.
Published: (2021-07-01)

Soluble plasma programmed death 1 (PD-1) and Tim-3 in primary HIV infection
by: Frater, J, et al.
Published: (2019)

Understanding participant perspectives around HIV-1 cure-related studies involving antiretroviral analytical treatment interruptions in the United Kingdom
by: Ming J. Lee, et al.
Published: (2023-12-01)

DNA/MVA Vaccination of HIV-1 Infected Participants with Viral Suppression on Antiretroviral Therapy, followed by Treatment Interruption: Elicitation of Immune Responses without Control of Re-Emergent Virus.
by: Melanie Thompson, et al.
Published: (2016-01-01)

Participant experiences in HIV cure-directed trial with an extended analytical treatment interruption in Philadelphia, United States
by: Andrea Bilger, et al.
Published: (2023-10-01)

HIV remission trial investigators’ attitudes towards risk and risk mitigation in trials that include treatment interruption
by: Eunice Akinyi Okumu, et al.
Published: (2023-06-01)

HIV reservoirs and immune surveillance evasion cause the failure of structured treatment interruptions : a computational study
by: Mancini, Emiliano, et al.
Published: (2013)