The role of astrocytes in CNS tumors: pre-clinical models and novel imaging approaches.
Brain metastasis is a significant clinical problem, yet the mechanisms governing tumor cell extravasation across the blood-brain barrier (BBB) and CNS colonization are unclear. Astrocytes are increasingly implicated in the pathogenesis of brain metastasis but in vitro work suggests both tumoricidal...
Main Authors: | O'Brien, E, Howarth, C, Sibson, N |
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Format: | Journal article |
Language: | English |
Published: |
2013
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