Synthesis, photolysis studies and in vitro photorelease of caged TRPV1 agonists and antagonists.
The synthesis of a range of caged TRPV1 agonists and antagonists is reported. The photolysis characteristics of these compounds, when irradiated with a 355 nm laser, have been studied and in all cases the desired compound was produced. Photolysis of a caged TRPV1 agonist in cultured trigeminal neuro...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2009
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| _version_ | 1826257936327901184 |
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| author | Ryssen, V Avlonitis, N Giniatullin, R McDougall, C Carr, J Stanton-Humphreys, M Borgström, E Brown, C Fayuk, D Surin, A Niittykoski, M Khiroug, L Conway, S |
| author_facet | Ryssen, V Avlonitis, N Giniatullin, R McDougall, C Carr, J Stanton-Humphreys, M Borgström, E Brown, C Fayuk, D Surin, A Niittykoski, M Khiroug, L Conway, S |
| author_sort | Ryssen, V |
| collection | OXFORD |
| description | The synthesis of a range of caged TRPV1 agonists and antagonists is reported. The photolysis characteristics of these compounds, when irradiated with a 355 nm laser, have been studied and in all cases the desired compound was produced. Photolysis of a caged TRPV1 agonist in cultured trigeminal neurons produced responses that were consistent with the activation of TRPV1 receptors. |
| first_indexed | 2024-03-06T18:26:05Z |
| format | Journal article |
| id | oxford-uuid:0800043b-88b5-4bf6-9ab2-d8fd017bbcb4 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T18:26:05Z |
| publishDate | 2009 |
| record_format | dspace |
| spelling | oxford-uuid:0800043b-88b5-4bf6-9ab2-d8fd017bbcb42022-03-26T09:10:41ZSynthesis, photolysis studies and in vitro photorelease of caged TRPV1 agonists and antagonists.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:0800043b-88b5-4bf6-9ab2-d8fd017bbcb4EnglishSymplectic Elements at Oxford2009Ryssen, VAvlonitis, NGiniatullin, RMcDougall, CCarr, JStanton-Humphreys, MBorgström, EBrown, CFayuk, DSurin, ANiittykoski, MKhiroug, LConway, SThe synthesis of a range of caged TRPV1 agonists and antagonists is reported. The photolysis characteristics of these compounds, when irradiated with a 355 nm laser, have been studied and in all cases the desired compound was produced. Photolysis of a caged TRPV1 agonist in cultured trigeminal neurons produced responses that were consistent with the activation of TRPV1 receptors. |
| spellingShingle | Ryssen, V Avlonitis, N Giniatullin, R McDougall, C Carr, J Stanton-Humphreys, M Borgström, E Brown, C Fayuk, D Surin, A Niittykoski, M Khiroug, L Conway, S Synthesis, photolysis studies and in vitro photorelease of caged TRPV1 agonists and antagonists. |
| title | Synthesis, photolysis studies and in vitro photorelease of caged TRPV1 agonists and antagonists. |
| title_full | Synthesis, photolysis studies and in vitro photorelease of caged TRPV1 agonists and antagonists. |
| title_fullStr | Synthesis, photolysis studies and in vitro photorelease of caged TRPV1 agonists and antagonists. |
| title_full_unstemmed | Synthesis, photolysis studies and in vitro photorelease of caged TRPV1 agonists and antagonists. |
| title_short | Synthesis, photolysis studies and in vitro photorelease of caged TRPV1 agonists and antagonists. |
| title_sort | synthesis photolysis studies and in vitro photorelease of caged trpv1 agonists and antagonists |
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