Allele-specific B pocket transplant in class I major histocompatibility complex protein changes requirement for anchor residue at P2 of peptide.

Allele-specific B pocket transplant in class I major histocompatibility complex protein changes requirement for anchor residue at P2 of peptide.

Ցույց տալ այլ տարբերակներ (1)

To investigate the role of an anchoring pocket in allele-specific peptide presentation by a major histocompatibility complex class I molecule, we "transplanted" a B pocket from HLA-A*0201 into HLA-B*2705 by site-directed mutagenesis. The resulting protein, designated B27.A2B, binds a diffe...

Ամբողջական նկարագրություն

Մատենագիտական մանրամասներ
Հիմնական հեղինակներ:	Colbert, R, Rowland-Jones, S, Mcmichael, A, Frelinger, J
Ձևաչափ:	Journal article
Լեզու:	English
Հրապարակվել է:	1993

Նմանատիպ նյութեր

Allele-specific B pocket transplant in class I major histocompatibility complex protein changes requirement for anchor residue at P2 of peptide.
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B-POCKET TRANSPLANT FROM HLA-A2 INTO B27 CHANGES REQUIREMENT FOR P-2 ANCHOR RESIDUE IN PEPTIDE PRESENTATION
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