The Longevity Med Summit: insights on healthspan from cell to society
In recent years, there has been a paradigm shift with regards to ageing, challenging its traditional perception as an inevitable and natural process. Researchers have collectively identified hallmarks of ageing, nine of which were initially proposed in 2013 and expanded in 2023 to include disabled m...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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Frontiers Media
2024
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| _version_ | 1811140205131857920 |
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| author | Falshaw, N Sagner, M Siow, RC |
| author_facet | Falshaw, N Sagner, M Siow, RC |
| author_sort | Falshaw, N |
| collection | OXFORD |
| description | In recent years, there has been a paradigm shift with regards to ageing, challenging its traditional perception as an inevitable and natural process. Researchers have collectively identified hallmarks of ageing, nine of which were initially proposed in 2013 and expanded in 2023 to include disabled macroautophagy, chronic inflammation, and dysbiosis, enhancing our understanding of the ageing process at microscopic, cellular, and system-wide levels. Strategies to manipulate these hallmarks present opportunities for slowing, preventing, or reversing age-related diseases, thereby promoting longevity. The interdependence of these hallmarks underscores the necessity of a comprehensive, systems-based approach to address the complex processes contributing to ageing. As a primary risk factor for various diseases, ageing diminishes healthspan, leading to extended periods of compromised health and multiple age-related conditions towards the end of life. The significant gap between healthspan and lifespan holds substantial economic and societal implications. The inaugural Longevity Med Summit (4–5 May 2023, Cascais, Portugal) provided an international forum to discuss the academic and industry landscape of healthy longevity research, preventive medicine and clinical practice to enhance healthspan. |
| first_indexed | 2024-09-25T04:18:17Z |
| format | Journal article |
| id | oxford-uuid:08193ac8-9ce6-47ed-98e3-1f98b2d1977b |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-09-25T04:18:17Z |
| publishDate | 2024 |
| publisher | Frontiers Media |
| record_format | dspace |
| spelling | oxford-uuid:08193ac8-9ce6-47ed-98e3-1f98b2d1977b2024-07-30T19:34:48ZThe Longevity Med Summit: insights on healthspan from cell to societyJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:08193ac8-9ce6-47ed-98e3-1f98b2d1977bEnglishJisc Publications RouterFrontiers Media2024Falshaw, NSagner, MSiow, RCIn recent years, there has been a paradigm shift with regards to ageing, challenging its traditional perception as an inevitable and natural process. Researchers have collectively identified hallmarks of ageing, nine of which were initially proposed in 2013 and expanded in 2023 to include disabled macroautophagy, chronic inflammation, and dysbiosis, enhancing our understanding of the ageing process at microscopic, cellular, and system-wide levels. Strategies to manipulate these hallmarks present opportunities for slowing, preventing, or reversing age-related diseases, thereby promoting longevity. The interdependence of these hallmarks underscores the necessity of a comprehensive, systems-based approach to address the complex processes contributing to ageing. As a primary risk factor for various diseases, ageing diminishes healthspan, leading to extended periods of compromised health and multiple age-related conditions towards the end of life. The significant gap between healthspan and lifespan holds substantial economic and societal implications. The inaugural Longevity Med Summit (4–5 May 2023, Cascais, Portugal) provided an international forum to discuss the academic and industry landscape of healthy longevity research, preventive medicine and clinical practice to enhance healthspan. |
| spellingShingle | Falshaw, N Sagner, M Siow, RC The Longevity Med Summit: insights on healthspan from cell to society |
| title | The Longevity Med Summit: insights on healthspan from cell to society |
| title_full | The Longevity Med Summit: insights on healthspan from cell to society |
| title_fullStr | The Longevity Med Summit: insights on healthspan from cell to society |
| title_full_unstemmed | The Longevity Med Summit: insights on healthspan from cell to society |
| title_short | The Longevity Med Summit: insights on healthspan from cell to society |
| title_sort | longevity med summit insights on healthspan from cell to society |
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