MRE11A isoform expression associated with outcome following radiotherapy in muscle-invasive bladder cancer does not alter cell survival and DNA double-strand break repair following ionising radiation

MRE11A isoform expression associated with outcome following radiotherapy in muscle-invasive bladder cancer does not alter cell survival and DNA double-strand break repair following ionising radiation

<p><strong>Background:</strong> DNA double strand breaks are the cytotoxic lesions produced by ionising radiation. Critical for the repair of these lesions is the DNA damage response protein MRE11 which, in a complex with RAD50 and NBS1, mediates DNA damage signalling and double-st...

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Bibliographic Details
Main Authors:	Walker, AK, Na, J, Browning, L, Humayun-Zakaria, N, Zeegers, MP, Cheng, KK, James, ND, Bryan, RT, Arnold, R, Kiltie, A
Format:	Journal article
Published:	IOS Press 2019

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