A Small Interfering RNA Screen of Genes Involved in DNA Repair Identifies Tumor-Specific Radiosensitization by POLQ Knockdown

Geahča maid

• A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown.
  Dahkki: Higgins, G, et al.
  Almmustuhtton: (2010)
• POLQ (DNA polyermase theta) as a novel therapeutic target: preclinical and clinical data
  Dahkki: Higgins, G, et al.
  Almmustuhtton: (2010)
• Overexpression of POLQ confers a poor prognosis in early breast cancer patients.
  Dahkki: Higgins, G, et al.
  Almmustuhtton: (2010)
• NVP-BEZ235 and NVP-BGT226, dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitors, enhance tumor and endothelial cell radiosensitivity.
  Dahkki: Fokas, E, et al.
  Almmustuhtton: (2012)
• POLQ knockdown inhibits proliferation, migration, and invasion by inducing cell cycle arrest in colorectal cancer
  Dahkki: Qing Yao, et al.
  Almmustuhtton: (2024-11-01)