Structure-activity relationship study of cytotoxic neolignan derivatives using multivariate analysis and computation-aided drug design.

Structure-activity relationship study of cytotoxic neolignan derivatives using multivariate analysis and computation-aided drug design.

Dehydrodieugenol B and five related natural neolignans were isolated from the Brazilian plant species Nectandra leucantha. Three of these compounds were shown to be active against murine (B16F10) and human (A2058) melanoma cells but non-toxic to human fibroblasts (T75). These results stimulated the...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	de Sousa, FS, Baldim, JL, Azevedo, RA, Figueiredo, CR, Pieper, P, Sear, CE, Anderson, EA, Lago, JHG
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	Elsevier 2020

Míreanna comhchosúla

Synthesis and structure–activity relationship of dehydrodieugenol B neolignans against Trypanosoma cruzi
de réir: Sear, CE, et al.
Foilsithe / Cruthaithe: (2020)

ISOLATION OF CYTOTOXIC NEOLIGNANS FROM Saururus cernuus L. (SAURURACEAE) USING IONIC LIQUID IN THE MICROWAVE ASSISTED EXTRACTION (MAE)
de réir: Juliana R. Brito, et al.

Synthesis of 2-aryldihydrobenzofuran neolignans and 2-arylbenzofuran neolignans and their larvicidal activities
de réir: Juhan, Siti Fadilah
Foilsithe / Cruthaithe: (2018)

Total synthesis of neolignans.
de réir: Mak, Ching-Pong
Foilsithe / Cruthaithe: (2006)

Chemical transformations of neolignans
de réir: Massayoshi Yoshida
Foilsithe / Cruthaithe: (1991-01-01)

The rational search for natural neolignans
de réir: Otto R. Gottlieb
Foilsithe / Cruthaithe: (1991-01-01)

Bioactivity of neolignans from fructus Schizandrae
de réir: Xiao-Yu Li
Foilsithe / Cruthaithe: (1991-01-01)

Antimycobacterial neolignans isolated from Aristolochia taliscana
de réir: Rosalba León-Díaz, et al.
Foilsithe / Cruthaithe: (2010-02-01)

Marine alkaloids as bioactive agents against protozoal neglected tropical diseases and malaria
de réir: Tempone, AG, et al.
Foilsithe / Cruthaithe: (2021)

A semi-synthetic neolignan derivative from dihydrodieugenol B selectively affects the bioenergetic system of Leishmania infantum and inhibits cell division
de réir: Amaral, M, et al.
Foilsithe / Cruthaithe: (2019)

Biosynthesis of tetrahydrobenzofuran neolignans in somatic embryos of Ocotea catharinensis
de réir: Érica Luiz dos Santos, et al.
Foilsithe / Cruthaithe: (2022-08-01)

Two New Neolignans from Syringa velutina Kom.
Foilsithe / Cruthaithe: (2009-02-01)

Biosynthesis of tetrahydrobenzofuran neolignans in somatic embryos of Ocotea catharinensis
de réir: Érica Luiz dos Santos, et al.
Foilsithe / Cruthaithe: (2022-08-01)

Synthesis of Bisphenol Neolignans Inspired by Honokiol as Antiproliferative Agents
de réir: Nunzio Cardullo, et al.
Foilsithe / Cruthaithe: (2020-02-01)

Chemical Structures of Lignans and Neolignans Isolated from Lauraceae
de réir: Ya Li, et al.
Foilsithe / Cruthaithe: (2018-11-01)

Neolignans isolated from twigs of Nectandra leucantha Ness & Mart (Lauraceae) displayed in vitro antileishmanial activity
de réir: Simone S Grecco, et al.
Foilsithe / Cruthaithe: (2018-09-01)

Isolation of new neolignans and an unusual meroterpenoid from Piper cabagranum
de réir: Celso R. de Oliveira, et al.
Foilsithe / Cruthaithe: (2024-01-01)

Reaction with ROO• and HOO• Radicals of Honokiol-Related Neolignan Antioxidants
de réir: Nunzio Cardullo, et al.
Foilsithe / Cruthaithe: (2023-01-01)

Flavonoids and a neolignan glucoside from Guarea macrophylla (Meliaceae)
de réir: Cristiane Pereira, et al.
Foilsithe / Cruthaithe: (2012-01-01)

A New Neolignan Glycoside from the Leaves of Acer truncatum
de réir: Hai-Yang Liu, et al.
Foilsithe / Cruthaithe: (2006-12-01)

Neolignans isolated from Saururus cernuus L. (Saururaceae) exhibit efficacy against Schistosoma mansoni
de réir: Juliana R. Brito, et al.
Foilsithe / Cruthaithe: (2022-11-01)

Seladoeneolignan A, a new neolignan from Selaginella doederleinii Hieron.
de réir: Minyu CHEN, et al.
Foilsithe / Cruthaithe: (2022-09-01)

A Synthetic View on Haedoxans and Related Neolignans From Phryma leptostachya
de réir: Yang Chen, et al.
Foilsithe / Cruthaithe: (2020-06-01)

Neuroprotective Potency of Neolignans in Magnolia officinalis Cortex Against Brain Disorders
de réir: Shun Zhu, et al.
Foilsithe / Cruthaithe: (2022-06-01)

Promotion of mammalian angiogenesis by neolignans derived from soybean extracellular fluids.
de réir: Farzaneh Kordbacheh, et al.
Foilsithe / Cruthaithe: (2018-01-01)

Neolignans and Norlignans from Insect Medicine Polyphaga plancyi and Their Biological Activities
de réir: Hong-Jie Zhu, et al.
Foilsithe / Cruthaithe: (2020-09-01)

New Neolignans and a Phenylpropanoid Glycoside from Twigs of Miliusa mollis
de réir: Kittisak Likhitwitayawuid, et al.
Foilsithe / Cruthaithe: (2010-01-01)

<i>Piper tectoniifolium</i> Kunth: A New Natural Source of the Bioactive Neolignan (−)-Grandisin
de réir: André M. Marques, et al.
Foilsithe / Cruthaithe: (2022-02-01)

Discovery of New Hits as Antitrypanosomal Agents by In Silico and In Vitro Assays Using Neolignan-Inspired Natural Products from <i>Nectandra leucantha</i>
de réir: Sheila C. Araujo, et al.
Foilsithe / Cruthaithe: (2021-07-01)

(+)-Kunstlerone, a New Antioxidant Neolignan from the Leaves of Beilschmiedia kunstleri Gamble
de réir: Mollataghi, A., et al.
Foilsithe / Cruthaithe: (2011)

(+)-Kunstlerone, a New Antioxidant Neolignan from the Leaves of Beilschmiedia kunstleri Gamble
de réir: Marc Litaudon, et al.
Foilsithe / Cruthaithe: (2011-08-01)

Trogopterins A–C: Three new neolignans from feces of Trogopterus xanthipes
de réir: Soyoon Baek, et al.
Foilsithe / Cruthaithe: (2014-12-01)

Biological activity and structure–activity relationship of dehydrodieugenol B analogues against visceral leishmaniasis
de réir: Amaral, M, et al.
Foilsithe / Cruthaithe: (2023)

Magnolol, a Neolignan-like Drug, Inhibits Porcine Epidemic Diarrhea Virus Replication in Cultured Cells
de réir: Xiaoting Wang, et al.
Foilsithe / Cruthaithe: (2023-02-01)

Neolignans and Diarylnonanoid Derivatives with Anti-inflammatory Activity from Myristica fragrans Houtt. Seeds
de réir: Tam Thi Le, et al.
Foilsithe / Cruthaithe: (2024-07-01)

Jatrolignans C and D: New Neolignan Epimers from <i>Jatropha curcas</i>
de réir: Yi-Lin He, et al.
Foilsithe / Cruthaithe: (2022-05-01)

Chemical Proteomics-Guided Identification of a Novel Biological Target of the Bioactive Neolignan Magnolol
de réir: Chiara Cassiano, et al.
Foilsithe / Cruthaithe: (2019-02-01)

A catechol-type lignan and neolignans are specifically present in the seed coat of tung trees
de réir: Toshisada Suzuki, et al.
Foilsithe / Cruthaithe: (2020-08-01)

A Structure-Activity Relationship (SAR) Study of Neolignan Compounds with Anti-schistosomiasis Activity
de réir: Alves Claúdio N., et al.
Foilsithe / Cruthaithe: (2002-01-01)

Anti-Inflamatory Activity of Neolignan Compound Isolated from the Roots of <i>Saururus chinensis</i>
de réir: Sae-Rom Yoo, et al.
Foilsithe / Cruthaithe: (2020-07-01)