ATM, ATR, and DNA-PK: The trinity at the heart of the DNA damage response
In vertebrate cells, the DNA damage response is controlled by three related kinases: ATM, ATR, and DNA-PK. It has been 20 years since the cloning of ATR, the last of the three to be identified. During this time, our understanding of how these kinases regulate DNA repair and associated events has gro...
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| Médium: | Journal article |
| Jazyk: | English |
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Cell Press
2017
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