Ser7 phosphorylation of the CTD recruits the RPAP2 Ser5 phosphatase to snRNA genes.

The carboxy-terminal domain (CTD) of the large subunit of RNA polymerase II (Pol II) comprises multiple heptapeptide repeats of the consensus Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Reversible phosphorylation of Ser2, Ser5, and Ser7 during the transcription cycle mediates the sequential recruitment of t...

Полное описание

Библиографические подробности
Главные авторы: Egloff, S, Zaborowska, J, Laitem, C, Kiss, T, Murphy, S
Формат: Journal article
Язык:English
Опубликовано: 2012