Interplay between DNA and histone methylation at an alpha-globin gene silenced by antisense RNA

Interplay between DNA and histone methylation at an alpha-globin gene silenced by antisense RNA

Bibliographic Details
Main Authors:	De Gobbi, M, Stanley, J, Ayyub, H, Wood, G, Higgs, D, Tufarelli, C
Format:	Conference item
Published:	2007

Similar Items

Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease.
by: Tufarelli, C, et al.
Published: (2003)

RNA mediated silencing and methylation of a non imprinted autosomal gene.
by: Tufarelli, C, et al.
Published: (2003)

The role of the polycomb complex in silencing alpha-globin gene expression in nonerythroid cells.
by: Garrick, D, et al.
Published: (2008)

Analysis of DNA Methylation at the Human Alpha Globin Cluster during Hematopoiesis
by: Ekwattanakit, S, et al.
Published: (2008)

Tissue-specific histone modification and transcription factor binding in alpha globin gene expression.
by: De Gobbi, M, et al.
Published: (2007)

The mechanism of alpha-globin activation during erythropoiesis
by: Higgs, D, et al.
Published: (2007)

Synergistic silencing of α-globin and induction of γ-globin by histone deacetylase inhibitor, vorinostat as a potential therapy for β-thalassaemia
by: Mettananda, S, et al.
Published: (2019)

The role of histone deacetylases in repressing alpha-globin gene expression in non-erythroid cells.
by: Garrick, D, et al.
Published: (2003)

Deletion of the mouse alpha-globin regulatory element (HS -26) has an unexpectedly mild phenotype.
by: Anguita, E, et al.
Published: (2002)

Deletion of the mouse alpha globin regulatory element (HS-26) has an unexpectedly mild phenotype.
by: Anguita, E, et al.
Published: (2003)

Identification of a conserved erythroid specific domain of histone acetylation across the alpha-globin gene cluster.
by: Anguita, E, et al.
Published: (2001)

Gene silencing through RNA interference and antisense strategies in the lung
by: Griesenbach, U, et al.
Published: (2003)

Selective silencing of α-globin by the histone demethylase inhibitor IOX1: A potentially new pathway for treatment of β-thalassemia
by: Mettananda, S, et al.
Published: (2016)

A novel deletion causing alpha thalassemia clarifies the importance of the major human alpha globin regulatory element.
by: Viprakasit, V, et al.
Published: (2006)

Molecular rearrangements of the human alpha-globin gene cluster.
by: Higgs, D, et al.
Published: (1985)

Establishment and maintenance of the DNA methylation pattern in the human alpha-globin cluster
by: Gaentzsch, R
Published: (2013)

Long-range regulation of alpha-globin gene expression.
by: Higgs, D, et al.
Published: (2008)

Reactivation of a developmentally silenced embryonic globin gene
by: King, AJ, et al.
Published: (2021)

Long-range regulation of alpha globin gene expression during erythropoiesis.
by: Higgs, D, et al.
Published: (2008)

Analysis of the human alpha globin upstream regulatory element (HS-40) in transgenic mice.
by: Sharpe, J, et al.
Published: (1992)

The mouse alpha-globin locus regulatory element.
by: Gourdon, G, et al.
Published: (1995)

Alpha-thalassemia caused by a large (62 kb) deletion upstream of the human alpha globin gene cluster.
by: Hatton, C, et al.
Published: (1990)

DNA looping in the alpha-globin locus
by: Canals-Hamann, A, et al.
Published: (2007)

Gene silencing by DNA methylation in haematological malignancies.
by: Boultwood, J, et al.
Published: (2007)

GEOGRAPHIC-DISTRIBUTION OF ALPHA-GLOBIN AND BETA-GLOBIN GENE-CLUSTER POLYMORPHISMS
by: Wainscoat, J, et al.
Published: (1989)

Differences in the patterns of transcription factor binding in the human and mouse alpha globin clusters point to potential differences in their regulation.
by: De Gobbi, M, et al.
Published: (2005)

Contrasting effects of alpha and beta globin regulatory elements on chromatin structure may be related to their different chromosomal environments.
by: Craddock, C, et al.
Published: (1995)

Analysis of the human alpha-globin gene cluster in transgenic mice.
by: Sharpe, J, et al.
Published: (1993)

Nucleotide sequence of the 3' terminal third of rabbit alpha-globin messenger RNA: comparison with human alpha-globin messenger RNA.
by: Proudfoot, N, et al.
Published: (1977)

Identification of a conserved erythroid specific domain of histone acetylation across the a globin gene cluster.
by: Anguita, E, et al.
Published: (2001)

De novo deletion within the telomeric region flanking the human alpha globin locus as a cause of alpha thalassaemia.
by: Viprakasit, V, et al.
Published: (2003)

Characterization of a widely expressed gene (LUC7-LIKE; LUC7L) defining the centromeric boundary of the human alpha-globin domain.
by: Tufarelli, C, et al.
Published: (2001)

A 16.5 kb deletion in the alpha globin cluster associated with an extremely mild phenotype
by: Rugless, M, et al.
Published: (2007)

Understanding alpha-globin gene regulation: Aiming to improve the management of thalassemia.
by: Higgs, D, et al.
Published: (2005)

A large deletion in the human alpha-globin cluster caused by a replication error is associated with an unexpectedly mild phenotype.
by: Rugless, M, et al.
Published: (2008)

Analysis of the human alpha-globin gene cluster reveals a highly informative genetic locus.
by: Higgs, D, et al.
Published: (1986)

Is there a role for CTCF binding sites in regulating the structure or function of the a globin gene cluster?
by: Anguita, E, et al.
Published: (2005)

Cis-acting sequences regulating expression of the human alpha-globin cluster lie within constitutively open chromatin.
by: Vyas, P, et al.
Published: (1992)

Wrangling RNA: Antisense oligonucleotides for neurological disorders
by: Talbot, K, et al.
Published: (2019)

The structure of a human alpha-globin pseudogene and its relationship to alpha-globin gene duplication.
by: Proudfoot, N, et al.
Published: (1980)