Simulating topological domains in human chromosomes with a fitting-free model

Simulating topological domains in human chromosomes with a fitting-free model

We discuss a polymer model for the 3D organization of human chromosomes. A chromosome is represented by a string of beads, with each bead being "colored" according to 1D bioinformatic data (e.g., chromatin state, histone modification, GC content). Individual spheres (representing bi- and m...

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Những tác giả chính:	Brackley, C, Michieletto, D, Mouvet, F, Johnson, J, Kelly, S, Cook, P, Marenduzzo, D
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	Taylor and Francis 2016

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