Simulating topological domains in human chromosomes with a fitting-free model

Simulating topological domains in human chromosomes with a fitting-free model

We discuss a polymer model for the 3D organization of human chromosomes. A chromosome is represented by a string of beads, with each bead being "colored" according to 1D bioinformatic data (e.g., chromatin state, histone modification, GC content). Individual spheres (representing bi- and m...

书目详细资料
Main Authors:	Brackley, C, Michieletto, D, Mouvet, F, Johnson, J, Kelly, S, Cook, P, Marenduzzo, D
格式:	Journal article
语言:	English
出版:	Taylor and Francis 2016

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