Pyocyanin degradation by a tautomerizing demethylase inhibits Pseudomonas aeruginosa biofilms

The opportunistic pathogen Pseudomonas aeruginosa produces colorful redox-active metabolites called phenazines, which underpin biofilm development, virulence and clinical outcomes. Though phenazines exist in many forms, the best studied is pyocyanin. Here, we describe pyocyanin demethylase (PodA), a...

Descripció completa

Dades bibliogràfiques
Autors principals: Costa, K, Glasser, N, Conway, S, Newman, D
Format: Journal article
Idioma:English
Publicat: American Association for the Advancement of Science 2017