Pyocyanin degradation by a tautomerizing demethylase inhibits Pseudomonas aeruginosa biofilms
The opportunistic pathogen Pseudomonas aeruginosa produces colorful redox-active metabolites called phenazines, which underpin biofilm development, virulence and clinical outcomes. Though phenazines exist in many forms, the best studied is pyocyanin. Here, we describe pyocyanin demethylase (PodA), a...
| Main Authors: | , , , |
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| 格式: | Journal article |
| 語言: | English |
| 出版: |
American Association for the Advancement of Science
2017
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