Beta-catenin expression and allelic loss at APC in sporadic colorectal carcinogenesis.

Beta-catenin expression and allelic loss at APC in sporadic colorectal carcinogenesis.

beta-catenin is involved in E-cadherin-mediated cell adhesion, intracellular signal transduction, and also interacts with adenomatous polyposis coli (APC) protein. We previously found that 31% of colorectal adenomas and 84% of carcinomas showed reduced membranous staining of beta-catenin, while 46%...

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Bibliographic Details
Main Authors:	Hao, X, Frayling, I, Willcocks, T, Han, W, Tomlinson, I, Pignatelli, M, Pretlow, T, Talbot, I
Format:	Journal article
Language:	English
Published:	2002

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