Beta-catenin expression and allelic loss at APC in sporadic colorectal carcinogenesis.
beta-catenin is involved in E-cadherin-mediated cell adhesion, intracellular signal transduction, and also interacts with adenomatous polyposis coli (APC) protein. We previously found that 31% of colorectal adenomas and 84% of carcinomas showed reduced membranous staining of beta-catenin, while 46%...
المؤلفون الرئيسيون: | Hao, X, Frayling, I, Willcocks, T, Han, W, Tomlinson, I, Pignatelli, M, Pretlow, T, Talbot, I |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2002
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مواد مشابهة
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Loss of heterozygosity at APC and beta-catenin expression in sporadic colorectal carcinogenesis
حسب: Hao, X, وآخرون
منشور في: (1998) -
The interactions of APC, E-cadherin and beta-catenin in tumour development and progression.
حسب: Ilyas, M, وآخرون
منشور في: (1997) -
Reciprocity between membranous and nuclear expression of beta-catenin in colorectal tumours.
حسب: Hao, X, وآخرون
منشور في: (1997) -
Chromosome 11q in sporadic colorectal carcinoma: patterns of allele loss and their significance for tumorigenesis.
حسب: Tomlinson, I, وآخرون
منشور في: (1996) -
Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumours.
حسب: Homfray, T, وآخرون
منشور في: (1998)