Selective and reversible inhibitors of ubiquitin-specific protease 7: a patent evaluation (WO2013030218).

The invention described in this review (WO2013030218) relates to compounds based on the quinazolin-4-one scaffold, their process of preparation and applications to inhibit the ubiquitin-specific protease 7 (USP7), a deubiquitinating enzyme (DUB), which is considered a potentially important new drug...

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Hlavní autor: Kessler, B
Médium: Journal article
Jazyk:English
Vydáno: Informa Healthcare 2014