Hypoxia-mediated regulation of DDX5 through decreased chromatin accessibility and post-translational targeting restricts R-loop accumulation
<p>Local hypoxia occurs in most solid tumors and is associated with aggressive disease and therapy resistance. Widespread changes in gene expression play a critical role in the biological response to hypoxia. However, most research has focused on hypoxia-inducible genes as opposed to those tha...
Main Authors: | Leszczynka, K, Dzwigonska, M, Estephan, H, Moehlenbrink, J, Bowler, E, Giaccia, A, Mieczkowski, J, Kaminska, B, Hammond, E |
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Format: | Journal article |
Language: | English |
Published: |
Wiley
2023
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