ADAMTS and ADAM metalloproteinases in osteoarthritis - looking beyond the ‘usual suspects’

<h4>Introduction</h4> <p>Matrix metalloproteinases and ‘aggrecanase’ ADAMTSs are well established to play key roles in osteoarthritis (OA) through degradation of extracellular matrix type II collagen and aggrecan, and are thus potential targets for development of OA therapies.<...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors: Yang, C, Chanalaris, A, Troeberg, L
Format: Journal article
Udgivet: Elsevier 2017